What is a COA?
A certificate of analysis tells you what is in a batch and how it was measured. How to read one, and how to check that it belongs to your vial.
- Purity
- ≥99% HPLC
- COA
- per batch
- Strength
- 10 mg
Melanotan-1
Melanotan-1 is a synthetic peptide of 13 amino acids, a linear analog of alpha-MSH with norleucine at 4 and D-phenylalanine at 7. Buy Melanotan-1 for laboratory research from PulseChem: 10 mg of lyophilized powder per vial, ≥99% purity by HPLC and a COA for every batch.
€47.49 incl. VAT · €39.25 excl. VAT
- Shipping from Europe
- 1–3 working days within Europe
In stock
Volume discount
- 1–4 unitsUnit price€47.49 per unit
- 5–9 units5% off€45.12 per unit
- 10+ units10% off€42.74 per unit
Research Use Only. For laboratory research use only (in vitro). Not for human or animal use. The products are not medicines, foods, or cosmetics. They are not intended to diagnose, treat, cure, or prevent any disease. The information on this website has not been evaluated by the EMA, the Romanian National Agency for Medicines and Medical Devices (ANMDMR), or the FDA. Read the RUO policy
How is a solution prepared?
This is how solutions are prepared in the lab.
Step 1 of 8: Disinfect
The stoppers of both vials are wiped with an alcohol swab.
- Disinfect. The stoppers of both vials are wiped with an alcohol swab.
- Draw up. The needle passes through the stopper of the bacteriostatic water and the plunger draws up liquid.
- Transfer. The liquid runs down the inside wall of the vial with powder.
- Mix. The vial is gently swirled until the solution is clear.
- Done. The solution is ready for use in research.
- Take sample. A new needle passes through the stopper and the plunger draws up part of the solution.
- Sample vial. The solution runs through the septum of the screw cap into a sample vial.
- Analyze. The sample vial goes into the autosampler; the instrument measures the solution in vitro.
For laboratory research use only (in vitro). Not for human or animal use.
Molecule
- Molecular formula
- C78H111N21O19
- Molecular mass
- 1,646.8 g/mol
Sequence: Ac-SYS[Nle]EH[D-Phe]RWGKPV-NH₂
- first residue (N-terminus)
- modified residue or group
Structure from PubChem, CID 16197727. Schematic in 3D, not a measured structure.
The chain of Melanotan-1
Schematic view of the chain. This is not a measured 3D structure.
Point to an amino acid or use the arrow keys to see its name.
Drag or use the arrow keys to rotate the diagram. Point to a bead to see the name of the amino acid.
- Hydrophobic
- Uncharged side chain that avoids water.
- Polar
- Uncharged side chain that binds water.
- Positively charged
- Basic side chain, positive at neutral pH.
- Negatively charged
- Acidic side chain, negative at neutral pH.
- Special (Gly, Pro, Cys)
- Help determine the shape of the chain; cysteine can form a bridge.
The chain has 13 amino acids, shown here from the N-terminus to the C-terminus. The N-terminus is acetylated, the C-terminus is an amide, and 1 building block is in the D-form. Calculated average molecular mass: 1,646.9 g/mol. Compare this figure with the mass on the certificate of analysis.
On the research map: Brain and pituitary Skin and hair
Batch and COA
The batch number is on the vial label. You can find the certificate of analysis for that batch on the Lab results page or request it from us.
Specifications
| Other names | MT-I, MT-1 |
|---|---|
| Contents | 10 mg per vial |
| Sequence | Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2 |
| Purity | ≥99% (HPLC) |
| Intended use | For laboratory research use only (RUO) |
About Melanotan-1
Buy Melanotan-1 from PulseChem
PulseChem supplies Melanotan-1 in sealed glass vials holding 10 mg of lyophilized (freeze-dried) powder. The label shows the strength and the batch number, so you can always match the vial to the right certificate of analysis.
Other names are MT-I and MT-1; if you are looking for MT-I for sale, this is the product. Anyone 18 or older who buys for laboratory research can order, as a guest or with an account, and confirms research use at checkout.
Origin and structure
Melanotan-1 is a linear peptide of the same length as alpha-MSH, with an acetyl group at the start and an amide at the end. Two building blocks are replaced: norleucine for methionine at position 4, and D-phenylalanine for phenylalanine at position 7. Sawyer, Hruby, Hadley and colleagues at the University of Arizona described this variant in 1980 in the Proceedings of the National Academy of Sciences.
Since 2014, the same compound has been the active ingredient of an authorized medicine in the EU. The Melanotan-1 from PulseChem is a research chemical, not a medicine.
Purity and COA for every batch
Every batch is analyzed by an external laboratory: HPLC measures purity (≥99%), mass spectrometry the identity. With 13 amino acids, Melanotan-1 is more than 600 g/mol heavier than Melanotan 2, so the two cannot be confused on the COA. The certificate for your batch number is under Lab results.
Storage and shipping
Store Melanotan-1 in the closed vial, cool, dry and dark, as the label and COA state. Shipments go out from Europe, insulated and tracked, plus a cold pack in warm weather. On working days, orders received and paid before 3 p.m. Central European time ship the same day; delivery takes 1–3 working days within Europe. EU only.
For laboratory research only, not for human or animal use.
Questions about Melanotan-1
Where can I buy Melanotan-1?
Melanotan-1 is available from PulseChem in this web shop. A 10 mg vial costs €47.49 including VAT, and Melanotan-1 is in stock. Anything you order and pay for before 3 p.m. Central European time on a working day goes out the same day; delivery takes 1–3 working days within Europe. Every batch has a COA.
How is the purity of Melanotan-1 tested?
An external laboratory measures the purity of Melanotan-1 for every batch by HPLC: ≥99%. Mass spectrometry confirms the identity; the measured mass must fit the open chain of 13 amino acids, with its acetyl group and amide. Both measurements are on the COA, found under Lab results.
How is Melanotan-1 shipped and stored?
After ordering, Melanotan-1 is sent from Europe, insulated and tracked; in warm weather a cold pack is included. Parcels go to EU addresses only, with a delivery time of 1–3 working days. In the lab, keep the vial closed, cool, dry and dark; the label and COA give the details.
What is the difference between Melanotan-1 and Melanotan 2?
Melanotan-1 has the full length of alpha-MSH: 13 amino acids, with only two building blocks replaced, norleucine at 4 and D-phenylalanine at 7. Melanotan 2 is shorter: 7 amino acids derived from positions 4 to 10, with a lactam bridge that closes six of them into a ring (PubChem CID 16197727 and 92432). As a result, Melanotan-1 is more than 600 g/mol heavier.
Background from the knowledge base
What does 99% purity mean?
A purity of 99% tells you about the composition of the peptide, not about the amount in the vial. What the number measures, and what it does not.
Why lyophilize?
Peptides are supplied as a freeze-dried powder because they break down quickly in solution. What happens during freeze-drying, and what it means for storage.
