What is a COA?
A certificate of analysis tells you what is in a batch and how it was measured. How to read one, and how to check that it belongs to your vial.
- Purity
- ≥99% HPLC
- COA
- per batch
- Strength
- 10 mg
Melanotan 2
Melanotan 2 is a synthetic peptide of 7 amino acids, a cyclic analog of a fragment of alpha-MSH with a lactam ring. Buy Melanotan 2 for laboratory research from PulseChem: 10 mg of lyophilized powder per vial, ≥99% purity by HPLC and a COA for every batch.
€57.45 incl. VAT · €47.48 excl. VAT
- Shipping from Europe
- 1–3 working days within Europe
In stock
Volume discount
- 1–4 unitsUnit price€57.45 per unit
- 5–9 units5% off€54.58 per unit
- 10+ units10% off€51.71 per unit
Research Use Only. For laboratory research use only (in vitro). Not for human or animal use. The products are not medicines, foods, or cosmetics. They are not intended to diagnose, treat, cure, or prevent any disease. The information on this website has not been evaluated by the EMA, the Romanian National Agency for Medicines and Medical Devices (ANMDMR), or the FDA. Read the RUO policy
How is a solution prepared?
This is how solutions are prepared in the lab.
Step 1 of 8: Disinfect
The stoppers of both vials are wiped with an alcohol swab.
- Disinfect. The stoppers of both vials are wiped with an alcohol swab.
- Draw up. The needle passes through the stopper of the bacteriostatic water and the plunger draws up liquid.
- Transfer. The liquid runs down the inside wall of the vial with powder.
- Mix. The vial is gently swirled until the solution is clear.
- Done. The solution is ready for use in research.
- Take sample. A new needle passes through the stopper and the plunger draws up part of the solution.
- Sample vial. The solution runs through the septum of the screw cap into a sample vial.
- Analyze. The sample vial goes into the autosampler; the instrument measures the solution in vitro.
For laboratory research use only (in vitro). Not for human or animal use.
Molecule
- Molecular formula
- C50H69N15O9
- Molecular mass
- 1,024.2 g/mol
Sequence: Ac-[Nle]DH[D-Phe]RWK-NH₂
- first residue (N-terminus)
- modified residue or group
- bridge
Structure from PubChem, CID 92432. Schematic in 3D, not a measured structure.
The chain of Melanotan 2
Schematic view of the chain. This is not a measured 3D structure.
Point to an amino acid or use the arrow keys to see its name.
Drag or use the arrow keys to rotate the diagram. Point to a bead to see the name of the amino acid.
- Hydrophobic
- Uncharged side chain that avoids water.
- Positively charged
- Basic side chain, positive at neutral pH.
- Negatively charged
- Acidic side chain, negative at neutral pH.
- Bridge
- A link between two positions in the chain.
The chain has 7 amino acids, shown here from the N-terminus to the C-terminus. The N-terminus is acetylated, the C-terminus is an amide, 1 building block is in the D-form, and there is 1 bridge within the chain. Calculated average molecular mass: 1,024.2 g/mol. Compare this figure with the mass on the certificate of analysis.
On the research map: Brain and pituitary Skin and hair
Batch and COA
The batch number is on the vial label. You can find the certificate of analysis for that batch on the Lab results page or request it from us.
Specifications
| Other names | MT-II, MT-2 |
|---|---|
| Contents | 10 mg per vial |
| Sequence | Ac-Nle-Asp(1)-His-D-Phe-Arg-Trp-Lys(1)-NH2 |
| Purity | ≥99% (HPLC) |
| Intended use | For laboratory research use only (RUO) |
About Melanotan 2
Buy Melanotan 2 from PulseChem
Each vial of Melanotan 2 holds 10 mg of lyophilized (freeze-dried) powder in sealed glass. The label states the strength and the batch number, matching the certificate of analysis for that batch.
The literature also calls the compound MT-II, so if you want MT-II for sale, this is it. Anyone aged 18 or over who buys for laboratory research can order, as a guest or with an account; at checkout you confirm research use.
Origin and structure
Melanotan 2 is a cyclic heptapeptide derived from positions 4 to 10 of alpha-MSH. Compared with the natural peptide, four building blocks are replaced: norleucine at 4, aspartic acid at 5, D-phenylalanine at 7 and lysine at 10. Aspartic acid and lysine together form the lactam bridge, and the chain ends in an amide. Al-Obeidi, Hruby and colleagues at the University of Arizona described this cyclic structure in 1989 in the Journal of Medicinal Chemistry.
Melanotan 2 is not authorized as a medicine anywhere.
Purity and COA for every batch
An external laboratory measures purity by HPLC (≥99%) and identity by mass spectrometry. The lactam bridge costs one molecule of water, so the ring form is about 18 g/mol lighter than the same open chain. The difference from PT-141, which ends in an acid, is only about 1 g/mol. The COA for your batch number is under Lab results.
Storage and shipping
Keep the vial closed, cool, dry and dark, following the label and COA. We ship from Europe, insulated and tracked; in warm weather a cold pack goes along. If your order is received and paid before 3 p.m. Central European time on a working day, it leaves the same day. Delivery takes 1–3 working days within Europe; EU only.
For laboratory research only, not for human or animal use.
Questions about Melanotan 2
Where can I buy Melanotan 2?
Melanotan 2 is available from PulseChem in this web shop. The 10 mg vial costs €57.45 including VAT, and Melanotan 2 is in stock. Orders received and paid before 3 p.m. Central European time on a working day leave the same day; delivery takes 1–3 working days within Europe. There is a COA for every batch.
What is in a vial of Melanotan 2?
A vial of Melanotan 2 contains 10 mg of lyophilized (freeze-dried) powder in sealed glass, with the strength and batch number on the label. Under Lab results, that number leads to the COA for the batch. The measured mass on it should fit the amide form of 1024.2 g/mol, not the acid form of PT-141.
Is Melanotan 2 a medicine?
No, Melanotan 2 is not authorized as a medicine anywhere. The Melanotan 2 from PulseChem is a research chemical, intended for laboratory research only and not for human or animal use. At checkout you confirm that you buy the product for that purpose only. See also RUO policy.
What is the difference between Melanotan 2 and Melanotan-1?
Melanotan 2 is cyclic and has 7 amino acids; Melanotan-1 is linear and has 13, as many as alpha-MSH. Both carry norleucine at position 4 and D-phenylalanine at position 7 (PubChem CID 92432 and 16197727). Melanotan 2 also has a lactam bridge that closes six of its seven building blocks into a ring, and it is more than 600 g/mol lighter.
Background from the knowledge base
What does 99% purity mean?
A purity of 99% tells you about the composition of the peptide, not about the amount in the vial. What the number measures, and what it does not.
Why lyophilize?
Peptides are supplied as a freeze-dried powder because they break down quickly in solution. What happens during freeze-drying, and what it means for storage.
