What is a COA?
A certificate of analysis tells you what is in a batch and how it was measured. How to read one, and how to check that it belongs to your vial.
- Purity
- ≥99% HPLC
- COA
- per batch
- Strength
- 10 mg
PT-141
Chemical name: Bremelanotide
PT-141 is a synthetic peptide of 7 amino acids with a lactam ring, also known as bremelanotide. Buy PT-141 for laboratory research from PulseChem: 10 mg of lyophilized powder per vial, ≥99% purity by HPLC and a COA for every batch.
€55.45 incl. VAT · €45.83 excl. VAT
- Shipping from Europe
- 1–3 working days within Europe
In stock
Volume discount
- 1–4 unitsUnit price€55.45 per unit
- 5–9 units5% off€52.68 per unit
- 10+ units10% off€49.91 per unit
Research Use Only. For laboratory research use only (in vitro). Not for human or animal use. The products are not medicines, foods, or cosmetics. They are not intended to diagnose, treat, cure, or prevent any disease. The information on this website has not been evaluated by the EMA, the Romanian National Agency for Medicines and Medical Devices (ANMDMR), or the FDA. Read the RUO policy
How is a solution prepared?
This is how solutions are prepared in the lab.
Step 1 of 8: Disinfect
The stoppers of both vials are wiped with an alcohol swab.
- Disinfect. The stoppers of both vials are wiped with an alcohol swab.
- Draw up. The needle passes through the stopper of the bacteriostatic water and the plunger draws up liquid.
- Transfer. The liquid runs down the inside wall of the vial with powder.
- Mix. The vial is gently swirled until the solution is clear.
- Done. The solution is ready for use in research.
- Take sample. A new needle passes through the stopper and the plunger draws up part of the solution.
- Sample vial. The solution runs through the septum of the screw cap into a sample vial.
- Analyze. The sample vial goes into the autosampler; the instrument measures the solution in vitro.
For laboratory research use only (in vitro). Not for human or animal use.
Molecule
Research area: Brain
- Molecular formula
- C50H68N14O10
- Molecular mass
- 1,025.2 g/mol
Sequence: Ac-[Nle]DH[D-Phe]RWK-OH
- first residue (N-terminus)
- modified residue or group
- bridge
Structure from PubChem, CID 9941379. Schematic in 3D, not a measured structure.
The chain of PT-141
Schematic view of the chain. This is not a measured 3D structure.
Point to an amino acid or use the arrow keys to see its name.
Drag or use the arrow keys to rotate the diagram. Point to a bead to see the name of the amino acid.
- Hydrophobic
- Uncharged side chain that avoids water.
- Positively charged
- Basic side chain, positive at neutral pH.
- Negatively charged
- Acidic side chain, negative at neutral pH.
- Bridge
- A link between two positions in the chain.
The chain has 7 amino acids, shown here from the N-terminus to the C-terminus. The N-terminus is acetylated, 1 building block is in the D-form, and there is 1 bridge within the chain. Calculated average molecular mass: 1,025.2 g/mol. Compare this figure with the mass on the certificate of analysis.
On the research map: Brain and pituitary
Batch and COA
The batch number is on the vial label. You can find the certificate of analysis for that batch on the Lab results page or request it from us.
Specifications
| Chemical name | Bremelanotide |
|---|---|
| Contents | 10 mg per vial |
| Sequence | Ac-Nle-Asp(1)-His-D-Phe-Arg-Trp-Lys(1)-OH |
| Purity | ≥99% (HPLC) |
| Intended use | For laboratory research use only (RUO) |
About PT-141
Buy PT-141 from PulseChem
A vial of PT-141 contains 10 mg of lyophilized (freeze-dried) powder in sealed glass. The label shows the strength and the batch number, which matches the number on the certificate of analysis.
Looking for bremelanotide for sale? PT-141 and bremelanotide are two names for the same compound. Anyone aged 18 or over who buys for laboratory research can order, as a guest or with an account, and research use is confirmed at checkout.
What is PT-141?
PT-141 is a cyclic heptapeptide. After an acetylated norleucine, a lactam bridge between aspartic acid and lysine closes the other six building blocks into a ring that includes a D-phenylalanine. The chain ends in a free acid group. Molinoff and colleagues at Palatin Technologies described PT-141 in 2003 in the Annals of the New York Academy of Sciences as a synthetic analog of alpha-MSH.
In the United States, bremelanotide has been the active ingredient of a prescription medicine since 2019 (FDA). The PT-141 from PulseChem is a research chemical, not a medicine.
Purity and COA for every batch
Every batch is tested externally: HPLC for purity (≥99%), mass spectrometry for identity. PT-141 and Melanotan 2 differ only at the end of the chain, acid versus amide, and therefore by only about 1 g/mol in mass. The measured mass on the COA should match the acid form. Look up the COA under Lab results.
Storage and shipping
Store PT-141 closed, cool, dry and dark, as the label and COA indicate. It ships from Europe in insulated packaging with track and trace, with a cold pack in warm weather. Received and paid before 3 p.m. Central European time on a working day means shipped the same day; delivery takes 1–3 working days within Europe. EU only.
For laboratory research only, not for human or animal use.
Questions about PT-141
Where can I buy PT-141?
PT-141 is available from PulseChem in this web shop. A 10 mg vial costs €55.45 including VAT, and PT-141 is in stock. Orders received and paid before 3 p.m. Central European time on a working day are shipped the same day; delivery takes 1–3 working days within Europe. Every batch has its own COA.
What is in a vial of PT-141?
A vial of PT-141 contains 10 mg of bremelanotide as a lyophilized (freeze-dried) powder in sealed glass. The label states the strength and the batch number. With that number you can look up the COA for the batch under Lab results, with purity and measured mass.
Is PT-141 a medicine?
The PT-141 from PulseChem is not a medicine but a research chemical, intended for laboratory research only. Bremelanotide has been the active ingredient of a prescription medicine in the United States since 2019, approved by the FDA. This powder is not prepared or authorized as a medicine. See RUO policy.
What is the difference between PT-141 and Melanotan 2?
PT-141 and Melanotan 2 share the same seven building blocks and the same lactam ring. The difference is at the end of the chain: PT-141 ends in a free acid group, Melanotan 2 in an amide (PubChem CID 9941379 and 92432). As a result the two differ by only about 1 g/mol in mass. The COA for the batch shows which form was measured.
Background from the knowledge base
What does 99% purity mean?
A purity of 99% tells you about the composition of the peptide, not about the amount in the vial. What the number measures, and what it does not.
Why lyophilize?
Peptides are supplied as a freeze-dried powder because they break down quickly in solution. What happens during freeze-drying, and what it means for storage.
