What is ipamorelin?
Ipamorelin is a synthetic five-residue peptide described as a selective agonist of the ghrelin receptor. Structure, its origin at Novo Nordisk, and its status.
- Purity
- ≥99% HPLC
- COA
- per batch
- Strength
- 10 mg
Ipamorelin
Ipamorelin is a synthetic peptide of 5 amino acids, three of which differ from the standard amino acids. Buy Ipamorelin for laboratory research from PulseChem: 10 mg of lyophilized powder per vial, ≥99% purity by HPLC and a COA for every batch.
€57.45 incl. VAT · €47.48 excl. VAT
- Shipping from Europe
- 1–3 working days within Europe
In stock
Volume discount
- 1–4 unitsUnit price€57.45 per unit
- 5–9 units5% off€54.58 per unit
- 10+ units10% off€51.71 per unit
Research Use Only. For laboratory research use only (in vitro). Not for human or animal use. The products are not medicines, foods, or cosmetics. They are not intended to diagnose, treat, cure, or prevent any disease. The information on this website has not been evaluated by the EMA, the Romanian National Agency for Medicines and Medical Devices (ANMDMR), or the FDA. Read the RUO policy
How is a solution prepared?
This is how solutions are prepared in the lab.
Step 1 of 8: Disinfect
The stoppers of both vials are wiped with an alcohol swab.
- Disinfect. The stoppers of both vials are wiped with an alcohol swab.
- Draw up. The needle passes through the stopper of the bacteriostatic water and the plunger draws up liquid.
- Transfer. The liquid runs down the inside wall of the vial with powder.
- Mix. The vial is gently swirled until the solution is clear.
- Done. The solution is ready for use in research.
- Take sample. A new needle passes through the stopper and the plunger draws up part of the solution.
- Sample vial. The solution runs through the septum of the screw cap into a sample vial.
- Analyze. The sample vial goes into the autosampler; the instrument measures the solution in vitro.
For laboratory research use only (in vitro). Not for human or animal use.
Molecule
Research area: Brain
- Molecular formula
- C38H49N9O5
- Molecular mass
- 711.9 g/mol
Sequence: H-[Aib]H[D-2Nal][D-Phe]K-NH₂
- first residue (N-terminus)
- modified residue or group
Structure from PubChem, CID 9831659. Schematic in 3D, not a measured structure.
The chain of Ipamorelin
Schematic view of the chain. This is not a measured 3D structure.
Point to an amino acid or use the arrow keys to see its name.
Drag or use the arrow keys to rotate the diagram. Point to a bead to see the name of the amino acid.
- Hydrophobic
- Uncharged side chain that avoids water.
- Positively charged
- Basic side chain, positive at neutral pH.
The chain has 5 amino acids, shown here from the N-terminus to the C-terminus. The C-terminus is an amide and 2 building blocks are in the D-form. Calculated average molecular mass: 711.9 g/mol. Compare this figure with the mass on the certificate of analysis.
On the research map: Brain and pituitary
Batch and COA
The batch number is on the vial label. You can find the certificate of analysis for that batch on the Lab results page or request it from us.
Specifications
| Contents | 10 mg per vial |
|---|---|
| Sequence | H-Aib-His-D-2Nal-D-Phe-Lys-NH2 |
| Purity | ≥99% (HPLC) |
| Intended use | For laboratory research use only (RUO) |
About Ipamorelin
Buy Ipamorelin from PulseChem
PulseChem supplies Ipamorelin in 10 mg vials: lyophilized (freeze-dried) powder in sealed glass. The label gives the strength and the batch number, so every vial can be traced to the certificate of analysis for its batch.
Ipamorelin for sale here can be ordered by anyone aged 18 or over who buys for laboratory research, as a guest or with an account; you confirm research use at checkout. Ipamorelin also comes in the blend CJC-1295 (no DAC) + Ipamorelin.
Structure of Ipamorelin
Ipamorelin is a pentapeptide with an amide at the end. Three of its five positions differ from the standard amino acids: 2-aminoisobutyric acid (Aib) and D-2-naphthylalanine are not in the genetic code, and D-phenylalanine is the mirror form of phenylalanine. That is why databases show its one-letter code with two X's.
The compound comes from peptide research at Novo Nordisk; Raun and colleagues described it in 1998 in the European Journal of Endocrinology. Ipamorelin is not authorized as a medicine anywhere. More in What is ipamorelin?
Purity and COA for every batch
Every batch goes to an external laboratory: HPLC determines purity (≥99%), mass spectrometry the identity. The two non-coded building blocks must be included in the calculated mass; a calculator that knows only the twenty standard amino acids gives the wrong value here. Find the COA for your batch under Lab results.
Storage and shipping
Store Ipamorelin in the closed vial, cool, dry and dark, as the label and COA state. Parcels ship from Europe, insulated and tracked; in warm weather a cold pack goes in. Orders received and paid before 3 p.m. Central European time on a working day ship the same day, and delivery takes 1–3 working days within Europe. EU only.
For laboratory research only, not for human or animal use.
Questions about Ipamorelin
Where can I buy Ipamorelin?
Ipamorelin is available from PulseChem in this web shop. A 10 mg vial costs €57.45 including VAT, and Ipamorelin is in stock. If your order is in and paid before 3 p.m. Central European time on a working day, it ships the same day; delivery takes 1–3 working days within Europe. Each batch has a COA.
How is the purity of Ipamorelin tested?
For Ipamorelin, an external laboratory measures purity by HPLC for every batch: ≥99%. Identity follows from mass spectrometry. With a molecular mass of just over 700 g/mol, this small peptide appears there mainly as a singly or doubly charged ion. Both measurements are on the COA, found under Lab results.
How is Ipamorelin shipped and stored?
Ipamorelin ships from Europe in insulated packaging with track and trace, with a cold pack in warm weather. Delivery is within the EU only and takes 1–3 working days. After arrival, keep the closed vial cool, dry and dark, following the instructions on the label and the COA.
Where does Ipamorelin come from?
Ipamorelin comes from peptide research at Novo Nordisk in Denmark, where it carried the internal code NNC 26-0161. Raun and colleagues described the development of ipamorelin in 1998 in the European Journal of Endocrinology. In the same year, Ankersen and colleagues described a series of peptides derived from ipamorelin in the Journal of Medicinal Chemistry.
Background from the knowledge base
What are peptides?
A peptide is a short chain of amino acids joined by peptide bonds. How peptides differ from proteins, which peptides occur in nature, and which items in the catalog are not peptides.
How are peptides made? Synthesis and purification
From solution-phase chemistry to Merrifield's solid support, the Fmoc cycle, where impurities come from, purification by preparative HPLC, and what counterions do to the weight.
