What is retatrutide?
Retatrutide (LY3437943) is an investigational Eli Lilly peptide that acts on the GIP, GLP-1, and glucagon receptors. Its structure, publications, the TRIUMPH phase 3 program, and its status.
- Purity
- ≥99% HPLC
- COA
- per batch
- Strength
- 5–60 mg
Retatrutide
Retatrutide is a synthetic peptide of 39 amino acids, developed by Eli Lilly under the code LY3437943. Buy Retatrutide for laboratory research from PulseChem: lyophilized powder in strengths from 5 to 60 mg, ≥99% purity by HPLC and a COA for every batch.
Price range: €40.95 through €248.45 incl. VAT
- Shipping from Europe
- 1–3 working days within Europe
Volume discount
- 1–4 unitsUnit price
- 5–9 units5% off
- 10+ units10% off
Research Use Only. For laboratory research use only (in vitro). Not for human or animal use. The products are not medicines, foods, or cosmetics. They are not intended to diagnose, treat, cure, or prevent any disease. The information on this website has not been evaluated by the EMA, the Romanian National Agency for Medicines and Medical Devices (ANMDMR), or the FDA. Read the RUO policy
How is a solution prepared?
This is how solutions are prepared in the lab.
Step 1 of 8: Disinfect
The stoppers of both vials are wiped with an alcohol swab.
- Disinfect. The stoppers of both vials are wiped with an alcohol swab.
- Draw up. The needle passes through the stopper of the bacteriostatic water and the plunger draws up liquid.
- Transfer. The liquid runs down the inside wall of the vial with powder.
- Mix. The vial is gently swirled until the solution is clear.
- Done. The solution is ready for use in research.
- Take sample. A new needle passes through the stopper and the plunger draws up part of the solution.
- Sample vial. The solution runs through the septum of the screw cap into a sample vial.
- Analyze. The sample vial goes into the autosampler; the instrument measures the solution in vitro.
For laboratory research use only (in vitro). Not for human or animal use.
Molecule
Research area: Metabolism Gut
- Molecular formula
- C221H342N46O68
- Molecular mass
- 4,731 g/mol
Sequence: H-Y[Aib]QGTFTSDYSI[aMeLeu]LDKKAQ[Aib]AFIEYLLEGGPSSGAPPPS-NH₂
- first residue (N-terminus)
- modified residue or group
Structure from PubChem, CID 171934787. Schematic in 3D, not a measured structure.
The chain of Retatrutide
Schematic view of the chain. This is not a measured 3D structure.
Point to an amino acid or use the arrow keys to see its name.
Drag or use the arrow keys to rotate the diagram. Point to a bead to see the name of the amino acid.
- Hydrophobic
- Uncharged side chain that avoids water.
- Polar
- Uncharged side chain that binds water.
- Positively charged
- Basic side chain, positive at neutral pH.
- Negatively charged
- Acidic side chain, negative at neutral pH.
- Special (Gly, Pro, Cys)
- Help determine the shape of the chain; cysteine can form a bridge.
The chain has 39 amino acids, shown here from the N-terminus to the C-terminus. The C-terminus is an amide and the side chain of Lys at position 17 carries icosanedioyl-gGlu-AEEA.
On the research map: Stomach, pancreas, and adipose tissue Gut and gut-brain axis
Batch and COA
The batch number is on the vial label. You can find the certificate of analysis for that batch on the Lab results page or request it from us.
Specifications
| Contents | 5 mg / 10 mg / 20 mg / 30 mg / 40 mg / 50 mg / 60 mg per vial |
|---|---|
| Sequence | H-Tyr-Aib-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-aMeLeu-Leu-Asp-Lys-Lys(icosanedioyl-gGlu-AEEA)-Ala-Gln-Aib-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 |
| Purity | ≥99% (HPLC) |
| Intended use | For laboratory research use only (RUO) |
About Retatrutide
Buy Retatrutide from PulseChem
Retatrutide for sale at PulseChem comes in seven strengths: 5, 10, 20, 30, 40, 50 and 60 mg per vial. Each sealed glass vial holds the compound as lyophilized powder, with the strength and batch number on the label. Prices start at €40.95.
Anyone aged 18 or over who buys for laboratory research can order, as a guest or with an account. You confirm research use at checkout.
What is Retatrutide?
Retatrutide is a lipidated peptide: a fatty acid chain is attached to one lysine, and three building blocks fall outside the twenty standard amino acids. Coskun and colleagues at Eli Lilly described it in 2022 in Cell Metabolism. They designed it as a single molecule for three receptors: those for GIP, GLP-1 and glucagon.
Its CAS number is 2381089-83-2. As of November 2026, Retatrutide is in phase 3 clinical research, without authorization as a medicine from the EMA or the FDA. Background and sources are in What is retatrutide?
Purity and COA for every batch
An external laboratory tests every batch of Retatrutide: HPLC for purity (≥99%) and mass spectrometry for identity. With electrospray ionization, a molecule of more than 4700 g/mol shows several peaks, one per charge state, which software converts back to a single mass. The batch number on your vial leads to the matching certificate on Lab results.
Storage and shipping
Keep the vials closed, cool, dry and dark, as the label and COA state. Your order travels in insulated packaging with tracking, with a cold pack in warm weather. We ship from Europe, within the EU only, and delivery takes 1–3 working days within Europe. Orders received and paid before 3 p.m. Central European time on a working day leave the same day.
For laboratory research only, not for human or animal use.
Questions about Retatrutide
Where can I buy Retatrutide?
Retatrutide is available from PulseChem in this web shop. Prices start at €40.95 including VAT for 5 mg, and Retatrutide is in stock. Orders received and paid before 3 p.m. Central European time on a working day ship the same day; delivery takes 1–3 working days within Europe. Every batch comes with its own COA.
What is in a vial of Retatrutide?
A vial of Retatrutide contains 5, 10, 20, 30, 40, 50 or 60 mg of the peptide as lyophilized powder, depending on the strength you choose. The glass vial is sealed. The label shows the strength and batch number, and the COA for that batch shows the purity and the identity check.
Who can order Retatrutide?
Retatrutide can be ordered by anyone aged 18 or over who buys it for laboratory research. You do not need an account, as guest checkout is available. At checkout, you confirm that the product is for laboratory research only. PulseChem ships within the European Union only.
Is Retatrutide a medicine?
Retatrutide is not an authorized medicine: as of November 2026 it is a compound in clinical research, without authorization from the EMA or the FDA. The Retatrutide from PulseChem is a research chemical, not the manufacturer's investigational product. Its status and the publications are covered in What is retatrutide?
Background from the knowledge base
What are peptides?
A peptide is a short chain of amino acids joined by peptide bonds. How peptides differ from proteins, which peptides occur in nature, and which items in the catalog are not peptides.
What is cagrilintide?
Cagrilintide is a synthetic, long-acting analogue of the peptide hormone amylin, developed by Novo Nordisk and still investigational. Structure, publications, CagriSema and status.
