What is a COA?
A certificate of analysis tells you what is in a batch and how it was measured. How to read one, and how to check that it belongs to your vial.
- Purity
- ≥99% HPLC
- COA
- per batch
- Strength
- 10 mg
Semax
Semax is a synthetic peptide of 7 amino acids: the fragment ACTH(4-7), extended with the sequence Pro-Gly-Pro. Buy Semax for laboratory research from PulseChem: each vial holds 10 mg of lyophilized powder, with ≥99% purity by HPLC and a COA for every batch.
€47.45 incl. VAT · €39.21 excl. VAT
- Shipping from Europe
- 1–3 working days within Europe
In stock
Volume discount
- 1–4 unitsUnit price€47.45 per unit
- 5–9 units5% off€45.08 per unit
- 10+ units10% off€42.71 per unit
Research Use Only. For laboratory research use only (in vitro). Not for human or animal use. The products are not medicines, foods, or cosmetics. They are not intended to diagnose, treat, cure, or prevent any disease. The information on this website has not been evaluated by the EMA, the Romanian National Agency for Medicines and Medical Devices (ANMDMR), or the FDA. Read the RUO policy
How is a solution prepared?
This is how solutions are prepared in the lab.
Step 1 of 8: Disinfect
The stoppers of both vials are wiped with an alcohol swab.
- Disinfect. The stoppers of both vials are wiped with an alcohol swab.
- Draw up. The needle passes through the stopper of the bacteriostatic water and the plunger draws up liquid.
- Transfer. The liquid runs down the inside wall of the vial with powder.
- Mix. The vial is gently swirled until the solution is clear.
- Done. The solution is ready for use in research.
- Take sample. A new needle passes through the stopper and the plunger draws up part of the solution.
- Sample vial. The solution runs through the septum of the screw cap into a sample vial.
- Analyze. The sample vial goes into the autosampler; the instrument measures the solution in vitro.
For laboratory research use only (in vitro). Not for human or animal use.
Molecule
Research area: Brain
- Molecular formula
- C37H51N9O10S
- Molecular mass
- 813.9 g/mol
Sequence: H-MEHFPGP-OH
- first residue (N-terminus)
Structure from PubChem, CID 9811102. Schematic in 3D, not a measured structure.
The chain of Semax
Schematic view of the chain. This is not a measured 3D structure.
Point to an amino acid or use the arrow keys to see its name.
Drag or use the arrow keys to rotate the diagram. Point to a bead to see the name of the amino acid.
- Hydrophobic
- Uncharged side chain that avoids water.
- Positively charged
- Basic side chain, positive at neutral pH.
- Negatively charged
- Acidic side chain, negative at neutral pH.
- Special (Gly, Pro, Cys)
- Help determine the shape of the chain; cysteine can form a bridge.
The chain has 7 amino acids, shown here from the N-terminus to the C-terminus. Calculated average molecular mass: 813.9 g/mol. Compare this figure with the mass on the certificate of analysis.
On the research map: Brain and pituitary
Batch and COA
The batch number is on the vial label. You can find the certificate of analysis for that batch on the Lab results page or request it from us.
Specifications
| Contents | 10 mg per vial |
|---|---|
| Sequence | H-Met-Glu-His-Phe-Pro-Gly-Pro-OH |
| Purity | ≥99% (HPLC) |
| Intended use | For laboratory research use only (RUO) |
About Semax
Buy Semax from PulseChem
Semax comes as a lyophilized (freeze-dried) powder in a sealed glass vial, 10 mg per vial. The batch number on the label is the same number as on the certificate of analysis for that batch.
Semax for sale at PulseChem can be ordered by anyone aged 18 or over who is buying for laboratory research, as a guest or with an account. You confirm research use at checkout.
What is Semax?
Semax is a heptapeptide that starts with amino acids 4 to 7 of ACTH, followed by proline, glycine and proline. The literature often calls it an analog of ACTH(4-10), for example in Dolotov and colleagues (Brain Research, 2006). The PubChem title states the structure more precisely: ACTH(4-7) with Pro-Gly-Pro.
Like Selank, Semax comes from the Institute of Molecular Genetics of the Russian Academy of Sciences in Moscow; a 2013 overview article by Kolomin and colleagues from that institute (Neuroscience & Medicine) covers both. PubChem lists the CAS number 80714-61-0.
Purity and COA for every batch
For every batch, an external laboratory determines purity by HPLC (≥99%) and identity by mass spectrometry. Semax starts with methionine, an amino acid that can oxidize. An oxidized variant weighs about 16 g/mol more (one oxygen atom), so it stands out in the mass spectrum. Find the COA by batch number on Lab results.
Storage and shipping
Closed, cool, dry and dark: that is how to keep the vial, following the label and COA. We ship from Europe in insulated packaging with tracking, with a cold pack in warm weather. Orders received and paid before 3 p.m. Central European time on a working day leave the same day, and delivery takes 1–3 working days within Europe. Delivery within the EU only.
For laboratory research only, not for human or animal use.
Questions about Semax
Where can I buy Semax?
Semax is available from PulseChem in this web shop. The 10 mg vial costs €47.45 including VAT, and Semax is in stock. If you order and pay before 3 p.m. Central European time on a working day, we ship the same day; delivery takes 1–3 working days within Europe. Every batch comes with a COA.
How is Semax shipped and stored?
Semax ships from Europe in insulated packaging with tracking, with a cold pack in warm weather. After delivery, keep the vial closed, cool, dry and dark, as the label and COA state. PulseChem delivers within the EU only, in 1–3 working days.
Who can order Semax?
Semax can be ordered by anyone aged 18 or over who is buying it for laboratory research. No account is needed, because the research peptides for sale at PulseChem can also be ordered as a guest. At checkout you confirm that Semax is intended for laboratory research only. Companies and institutions can apply for a business account.
What is the difference between Semax and Selank?
Semax and Selank share the same end, Pro-Gly-Pro, but start differently. Semax begins with ACTH(4-7) (Met-Glu-His-Phe), Selank with tuftsin (Thr-Lys-Pro-Arg). Both are heptapeptides from the Institute of Molecular Genetics in Moscow. In the mass spectrum they lie more than 60 g/mol apart, so the COA tells them apart directly.
Background from the knowledge base
What does 99% purity mean?
A purity of 99% tells you about the composition of the peptide, not about the amount in the vial. What the number measures, and what it does not.
Why lyophilize?
Peptides are supplied as a freeze-dried powder because they break down quickly in solution. What happens during freeze-drying, and what it means for storage.
