What is KPV?
KPV is the tripeptide lysine-proline-valine, the last three amino acids of alpha-MSH. Structure, a pitfall when searching databases, the research and the status.
- Purity
- ≥99% HPLC
- COA
- per batch
- Strength
- 10 mg
KPV
KPV is a synthetic peptide of 3 amino acids, lysine, proline and valine, matching the end of alpha-MSH. Buy KPV for laboratory research from PulseChem: 10 mg of lyophilized powder per vial, ≥99% purity by HPLC and a COA for each batch.
€57.45 incl. VAT · €47.48 excl. VAT
- Shipping from Europe
- 1–3 working days within Europe
In stock
Volume discount
- 1–4 unitsUnit price€57.45 per unit
- 5–9 units5% off€54.58 per unit
- 10+ units10% off€51.71 per unit
Research Use Only. For laboratory research use only (in vitro). Not for human or animal use. The products are not medicines, foods, or cosmetics. They are not intended to diagnose, treat, cure, or prevent any disease. The information on this website has not been evaluated by the EMA, the Romanian National Agency for Medicines and Medical Devices (ANMDMR), or the FDA. Read the RUO policy
How is a solution prepared?
This is how solutions are prepared in the lab.
Step 1 of 8: Disinfect
The stoppers of both vials are wiped with an alcohol swab.
- Disinfect. The stoppers of both vials are wiped with an alcohol swab.
- Draw up. The needle passes through the stopper of the bacteriostatic water and the plunger draws up liquid.
- Transfer. The liquid runs down the inside wall of the vial with powder.
- Mix. The vial is gently swirled until the solution is clear.
- Done. The solution is ready for use in research.
- Take sample. A new needle passes through the stopper and the plunger draws up part of the solution.
- Sample vial. The solution runs through the septum of the screw cap into a sample vial.
- Analyze. The sample vial goes into the autosampler; the instrument measures the solution in vitro.
For laboratory research use only (in vitro). Not for human or animal use.
Molecule
Research area: Immune Gut Skin
- Molecular formula
- C16H30N4O4
- Molecular mass
- 342.43 g/mol
Sequence: H-KPV-OH
- first residue (N-terminus)
Structure from PubChem, CID 125672. As a 3D conformer computed by PubChem.
The chain of KPV
Schematic view of the chain. This is not a measured 3D structure.
Point to an amino acid or use the arrow keys to see its name.
Drag or use the arrow keys to rotate the diagram. Point to a bead to see the name of the amino acid.
- Hydrophobic
- Uncharged side chain that avoids water.
- Positively charged
- Basic side chain, positive at neutral pH.
- Special (Gly, Pro, Cys)
- Help determine the shape of the chain; cysteine can form a bridge.
The chain has 3 amino acids, shown here from the N-terminus to the C-terminus. Calculated average molecular mass: 342.4 g/mol. Compare this figure with the mass on the certificate of analysis.
On the research map: Immune system Gut and gut-brain axis Skin and hair
Batch and COA
The batch number is on the vial label. You can find the certificate of analysis for that batch on the Lab results page or request it from us.
Specifications
| Contents | 10 mg per vial |
|---|---|
| Sequence | H-Lys-Pro-Val-OH |
| Purity | ≥99% (HPLC) |
| Intended use | For laboratory research use only (RUO) |
About KPV
Buy KPV from PulseChem
A vial of KPV contains 10 mg of lyophilized (freeze-dried) powder, sealed in glass. The batch number on the label links the vial to the certificate of analysis of that batch.
You will find KPV for sale here for guests and account holders alike. Anyone aged 18 or over who is buying for laboratory research can order and confirms research use at checkout. KPV is also part of the Klow blend.
Origin of KPV
KPV is a tripeptide; its name is the one-letter code of its three amino acids. PubChem titles the record MSH (11-13): these are the last three amino acids of alpha-MSH, a peptide of 13 amino acids. One difference: alpha-MSH ends in an amide, KPV in a free acid. Searching PubChem for the name KPV alone leads to a different substance; CAS number 67727-97-3 avoids that confusion. KPV is not an authorized medicine. More in What is KPV?
Purity and COA for every batch
An external laboratory measures purity by HPLC (≥99%) and identity by mass spectrometry. For KPV, mass alone does not prove the order, because Val-Pro-Lys weighs exactly the same. That calls for the HPLC retention time or fragments in MS/MS. The COA for your batch number is on Lab results.
Storage and shipping
Store the closed vial cool, dry and dark, as the label and COA state. We send KPV from Europe in insulated packaging with tracking and add a cold pack in warm weather. Orders received and paid before 3 p.m. Central European time on a working day go out that day; delivery takes 1–3 working days within Europe. We deliver within the EU only.
For laboratory research only, not for human or animal use.
Questions about KPV
Where can I buy KPV?
KPV is available from PulseChem in this web shop. A 10 mg vial costs €57.45 including VAT, and KPV is in stock. If you order and pay before 3 p.m. Central European time on a working day, we ship the same day; delivery takes 1–3 working days within Europe. There is a COA for every batch.
How is the purity of KPV tested?
The purity of KPV is measured per batch by an external laboratory using HPLC, with release at ≥99%. Mass spectrometry confirms the mass but not the order, since a tripeptide with the same three amino acids in a different order weighs the same. The order is shown by the HPLC retention time or by fragments in MS/MS. The COA is on Lab results.
Who can order KPV?
KPV can be ordered by anyone aged 18 or over who buys it for laboratory research. PulseChem has research peptides for sale to guests as well as account holders. At checkout you confirm that KPV is for laboratory research only.
Where does KPV come from?
KPV comes from the peptide alpha-MSH: it consists of its last three amino acids, positions 11 to 13. That is why PubChem titles the record MSH (11-13). KPV itself is made synthetically and, unlike alpha-MSH, ends in a free acid rather than an amide.
Background from the knowledge base
What are peptides?
A peptide is a short chain of amino acids joined by peptide bonds. How peptides differ from proteins, which peptides occur in nature, and which items in the catalog are not peptides.
Peptide blends: reading the label and the COA
A blend is one vial holding two or more compounds in a fixed ratio. How the label states the amount, how such a mixture is measured, and what belongs on its certificate.
